- Mohnish Behl ... Dr. Ashutosh
Male Protaganist. Dr. Ashutosh is a quiet & serious person whose life entirely revolves around his career as a doctor, the hospital and its patients, and nothing else. He is kind to all but does not share his thoughts or feelings with anyone. Though Dr. Mallika, whom he's been friends with for 12 years, is in love with him, Ashutosh is oblivious to her feelings and views her as only a friend. There is no romance in his life; he lives alone and is quite content, if not bothered, by his loneliness. Ashutosh bereaves the death of his foster father, who had played a very big role in his life. However, he has no idea that his father also had a daughter, and that she gave birth to a girl who lives somewhere in the same city.
In his will, Ashutosh's father leaves behind everything but the house to Ashutosh. The house he leaves to his granddaughter whom Ashutosh never met. Ashutosh, while reminiscing his encounters with his father, gathers the true meaning of his father's two-sided replies. Ashutosh expects a responsible and mature person to take over his father's home. From the time he meets Nidhi, he plans to educate her behavior, although he does not realize exactly what it is that attracts and pulls him to Nidhi so much. Later he comes to realize that he is in love with Nidhi.
- Kritika Kamra ... Dr. Nidhi Verma
Female Protaganist. Nidhi is a cheerful, bubbly doctor who brings joy and laughter to the mundane life at the hospital, its patients, and in the life of Ashutosh . Nidhi never wanted to be a doctor but is told that her dying grandfather and mother both wanted her to be one. A phone call that her father attends explains that she just inherited a house that belonged to her grandfather. Seeing that her father wants her to become a doctor to celebrate her dead mother's wishes, Nidhi comes in as an intern at Ashutosh's hospital. She wins over the patients and the hospital staff with her humor and kindness. She falls in love with Ashutosh. Under her family's pressure, she will agree to marry Rohan despite being in love with Ashutosh.
- Karan Wahi... Rohan
Rohan is a cheerful and kind person who brings happiness to other people's life. He is a relative of Nidhi's DadiBua . He falls in one sided love with Nidhi, but when he comes to know that Nidhi has affections only for Ashutosh, he will be in a state of mind whether to help her or not.
- Vishal Malhotra ... Dr. Ranganath
- Ishita Sharma ... Anjalika (Anji) Solanki
- Alok Nath ... Dr. Mathur
- Rukhsar Rehman ... Dr. Mallika
- Vijay Kashyap ... Col. Yograj Verma
- Tanya Abrol ... Phoolan
- Amardeep Jha ... Nurse D'souza
- Nandita Puri ... Shyama Solanki
- Sheeba Chaddha ... Sanjeevani
- Kavita Vaid ... Daadi Bua
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